This webinar will provide an overview of data science, including machine learning and optimization, and present a few applications in the context of Smart Grid. Professor El Ghaoui will describe work done in collaboration with different units at EDF. Some of the topics reviewed include: a)text analytics for business intelligence on smart grid applications; b) advanced machine learning and optimization for co-generation intra-day plant management, and c) optimal design of complex smart grid systems using surrogate models.